Perspectives of nano-carrier drug delivery systems to overcome cancer drug resistance in the clinics.

ABSTRACT: Advanced cancer is still considered an incurable disease because of its metastatic spread to distal organs and progressive gain of chemoresistance. Even though considerable treatment progress and more effective therapies have been achieved over the past years, recurrence in the long-term and undesired side effects are still the main drawbacks of current clinical protocols. Moreover, a majority of chemotherapeutic drugs are highly hydrophobic and need to be diluted in organic solvents, which cause high toxicity, in order to reach effective therapeutic dose. These limitations of conventional cancer therapies prompted the use of nanomedicine, the medical application of nanotechnology, to provide more effective and safer cancer treatment. Potential of nanomedicines to overcome resistance, amel

SUBMITTER: Ulldemolins A 

PROVIDER: S-EPMC9019183 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature