Association between cigarette smoking and Parkinson's disease: a neuroimaging study.

ABSTRACT:

Background

Mounting evidence has revealed an inverse association between cigarette smoking and the risk of Parkinson's disease (PD). Meanwhile, cigarette smoking has been found to be associated with cognitive impairment in PD patients. However, the neural mechanisms of the association between cigarette smoking and PD are not fully understood.

Objective

The aim of this study is to explore the neural mechanisms of the association between cigarette smoking and PD.

Methods

A total of 129 PD patients and 69 controls were recruited from the Parkinson's Progression Markers Initiative (PPMI) cohort, including 39 PD patients with regular smoking history (PD-S), 90 PD patients without regular smoking history (PD-NS), 26 healthy controls with regular smoking history (HC-S), and

SUBMITTER: Wang C 

PROVIDER: S-EPMC9019319 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature