Ethical considerations around volunteer payments in a malaria human infection study in Kenya: an embedded empirical ethics study.

ABSTRACT: Human Infection Studies (HIS) have emerged as an important research approach with the potential to fast track the global development of vaccines and treatments for infectious diseases, including in low resource settings. Given the high level of burdens involved in many HIS, particularly prolonged residency and biological sampling requirements, it can be challenging to identify levels of study payments that provide adequate compensation but avoid 'undue' levels of inducement to participate. Through this embedded ethics study, involving 97 healthy volunteers and other research stakeholders in a malaria HIS programme in Kenya, and using in-depth interviews, focus group discussions and observations during and after a malaria HIS, we give a grounded account of ethical issues emerging in relatio

SUBMITTER: Chi PC 

PROVIDER: S-EPMC9019790 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature