Cognitive performance in systemic lupus erythematosus patients: a cross-sectional and longitudinal study.

ABSTRACT:

Background

Previous research has provided evidence for cognitive dysfunction as a common symptom of systemic lupus erythematosus (SLE). In light of this, the primary goal of this study was to investigate how cognitive impairment in this patient group develops over time. In addition, the present dataset contributes to delineating the specific abilities that are impaired in SLE patients as well as answering the question whether the disease affects the cognition of SLE patients with neuropsychiatric manifestations (NPSLE) and without (non-NPSLE) in distinct ways.

Methods

91 female participants (33 NPSLE, 29 non-NPSLE, 29 healthy controls (HC)) underwent standardized neurocognitive testing. A total of ten different cognitive abilities were assessed, among others executive functi

SUBMITTER: Langensee L 

PROVIDER: S-EPMC9019974 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature