Do sample size calculations in longitudinal orthodontic trials use the advantages of this study design?

ABSTRACT:

Objectives

To examine whether optimal calculations of the sample size are being used in longitudinal orthodontic trials.

Materials and methods

Longitudinal orthodontic trials with a minimum of three time points of outcome assessment published between January 1, 2017, and December 30, 2020, were sourced from a single electronic database. Study characteristics at the level of each trial were undertaken independently and in duplicate. Descriptive statistics and summary values were calculated. Inferential statistics (Fisher's exact test and logistic regression) were applied to detect associations between reporting of a sample size calculation and the study characteristics.

Results

A total of 147 trials were analyzed; 75.5% of these trials reported a sample size calculatio

SUBMITTER: Mheissen S 

PROVIDER: S-EPMC9020395 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature