The Implications of Treatment Delays in Adjuvant Therapy for Resected Cholangiocarcinoma Patients.

ABSTRACT:

Purpose

The purpose of this study is to understand factors associated with timing of adjuvant therapy for cholangiocarcinoma and the impact of delays on overall survival (OS).

Methods

Data from the National Cancer Database (NCDB) for patients with non-metastatic bile duct cancer from 2004 to 2015 were analyzed. Patients were included only if they underwent surgery and adjuvant chemotherapy and/or radiotherapy (RT). Patients who underwent neoadjuvant or palliative treatments were excluded. Pearson's chi-squared test and multivariate logistic regression analyses were used to assess the distribution of demographic, clinical, and treatment factors. After propensity score matching with inverse probability of treatment weighting, OS was compared between patients initiating therapy

SUBMITTER: Parsons M 

PROVIDER: S-EPMC9020757 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature