Is adjuvant chemotherapy necessary in older patients with breast cancer?

ABSTRACT:

Background

Due to the lack of clinical trials on the efficacy of chemotherapy in older patients, an optimal treatment strategy has not been developed. We investigated whether adjuvant chemotherapy could improve the survival of older patients with breast cancer in Japan.

Methods

We retrospectively analyzed data of patients with breast cancer aged ≥ 70 years who underwent breast cancer surgery in eight hospitals between 2008 and 2013. Clinical treatment and follow-up data were obtained from the patients' medical electric records.

Results

A total of 1095 patients were enrolled, of which 905 were included in the initial non-matched analysis. The median age and follow-up period were 75 (range 70-93) and 6.3 years, respectively. Of these patients, 127 (14%) received adjuvan

SUBMITTER: Morita M 

PROVIDER: S-EPMC9021076 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature