Association Between Platelet Levels and 28-Day Mortality in Patients With Sepsis: A Retrospective Analysis of a Large Clinical Database MIMIC-IV.

ABSTRACT:

Background

This research focused on evaluating the correlation between platelet count and sepsis prognosis, and even the dose-response relationship, in a cohort of American adults.

Method

Platelet counts were recorded retrospectively after hospitalization for patients admitted to Beth Israel Deaconess Medical Center's intensive care unit between 2008 and 2019. On admission to the intensive care unit, sepsis patients were divided into four categories based on platelet counts (very low < 50 × 10⁹/L, intermediate-low 50 × 10⁹-100 × 10⁹/L, low 100 × 10⁹-150 × 10⁹/L, and normal ≥ 150 × 10⁹/L). A multivariate Cox proportional risk model was used to calculate the 28-day risk of mortality in sepsis based on baseline p

SUBMITTER: Wang D 

PROVIDER: S-EPMC9021789 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature