Recurrent Duplication and Diversification of Acrosomal Fertilization Proteins in Abalone.

ABSTRACT: Reproductive proteins mediating fertilization commonly exhibit rapid sequence diversification driven by positive selection. This pattern has been observed among nearly all taxonomic groups, including mammals, invertebrates, and plants, and is remarkable given the essential nature of the molecular interactions mediating fertilization. Gene duplication is another important mechanism that facilitates the generation of molecular novelty through functional divergence. Following duplication, paralogs may partition ancestral gene function (subfunctionalization) or acquire new roles (neofunctionalization). However, the contributions of duplication followed by sequence diversification to the molecular diversity of gamete recognition genes has been understudied in many models of fertilization. The m

SUBMITTER: Carlisle JA 

PROVIDER: S-EPMC9022041 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature