Cost-effectiveness of pharmacological therapies for people with Alzheimer's disease and other dementias: a systematic review and meta-analysis.

ABSTRACT:

Objectives

This study aims to synthesize the empirical economic evidence of pharmaceutical therapies for people with dementia.

Study design

Systematic review and meta-analysis. Literature evaluating the costs and effects of drug therapies for dementia was indexed until December 2021. Quality of study was assessed using the Cochrane Risk of Bias Tool and Consensus on Health Economic Criteria list. Cost data were standardized to 2020 US dollars and analyzed from healthcare service and societal perspectives. Random-effects models were used to synthesize economic and clinical data, based on mean differences (MDs) and standardized MDs.

Results

Ten unique studies were identified from 11,771 records. Acetylcholinesterase inhibitors (AChEIs) and memantine improved dementia-re

SUBMITTER: Huo Z 

PROVIDER: S-EPMC9022294 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature