Treatment results for patients with squamous-cell carcinoma of the anus, a single institution retrospective analysis.

ABSTRACT:

Background and purpose

To gain insight into the treatment outcomes for anal cancer a retrospective analysis was performed with a special emphasis on trends in outcome and toxicities over time and on treatment of elderly patients.

Materials and methods

Medical records of 98 consecutive patients with squamous cell carcinoma of the anus of all stages treated with curative intent between 01-01-2009 and 31-12-2018 were analyzed with follow up until 31-12-2020. Standard tumor and pathological lymph node dose were 59.4 Gy (median 59.4 Gy, range 59.4-70 Gy) or 60 Gy (no deviation from intended dose), elective nodal regions were treated with 45 Gy (no deviations). Radiotherapy techniques in this period evolved from 3D-conformal to IMRT and VMAT. In 23 patients electron beams were use

SUBMITTER: Neelis KJ 

PROVIDER: S-EPMC9022342 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature