Randomized comparison of three high-flux dialyzers during high-volume online hemodiafiltration-the comPERFORM study.

ABSTRACT:

Background

Dialyzers should be designed to efficiently eliminate uraemic toxins during dialysis treatment, given that the accumulation of small and middle molecular weight uraemic solutes is associated with increased mortality risk of patients with end-stage renal disease. In the present study we investigated the novel FX CorAL dialyzer with a modified membrane surface for performance during online hemodiafiltration (HDF) in a clinical setting.

Methods

comPERFORM was a prospective, open, controlled, multicentric, interventional, crossover study with randomized treatment sequences. It randomized stable patients receiving regular post-dilution online HDF to FX CorAL 600 (Fresenius Medical Care Deutschland), xevonta Hi 15 (B. Braun) and ELISIO 150H (Nipro) each for 1 week. The

SUBMITTER: Ehlerding G 

PROVIDER: S-EPMC9022458 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature