Chemical mixture exposures during pregnancy and cognitive abilities in school-aged children.

ABSTRACT:

Introduction

Gestational exposure to chemical mixtures, which is prevalent among pregnant women, may be associated with adverse childhood neurodevelopment. However, few studies have examined relations between gestational chemical mixture exposure and children's cognitive abilities.

Methods

In a cohort of 253 pregnant women and their children from Cincinnati, OH (enrolled 2003-2006), we quantified biomarker concentrations of 43 metals, phthalates, phenols, polybrominated diphenyl ethers, organophosphate and organochlorine pesticides, polychlorinated biphenyls, perfluoroalkyl substances, and environmental tobacco smoke in blood or urine. Using k-means clustering and principal component (PC) analysis, we characterized chemical mixtures among pregnant women. We assessed children

SUBMITTER: Kalloo G 

PROVIDER: S-EPMC9022783 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature