A novel algorithm for cardiovascular screening using conjunctival microcirculatory parameters and blood biomarkers.

ABSTRACT: Microvascular haemodynamic alterations are associated with coronary artery disease (CAD). The conjunctival microcirculation can easily be assessed non-invasively. However, the microcirculation of the conjunctiva has not been previously explored in clinical algorithms aimed at identifying patients with CAD. This case-control study involved 66 patients with post-myocardial infarction and 66 gender-matched healthy controls. Haemodynamic properties of the conjunctival microcirculation were assessed with a validated iPhone and slit lamp-based imaging tool. Haemodynamic properties were extracted with semi-automated software and compared between groups. Biomarkers implicated in the development of CAD were assessed in combination with conjunctival microcirculatory parameters. The conjunctival bloo

SUBMITTER: Awuah A 

PROVIDER: S-EPMC9023476 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature