Relationships between retinopathy of prematurity without ophthalmologic intervention and neurodevelopment and vision at 2 years.

ABSTRACT:

Background

Severe retinopathy of prematurity (ROP) is associated with adverse outcomes. Relationships between milder ROP and outcomes have not been defined. We hypothesized that children with ROP stage ≤3 who did not receive ophthalmologic intervention would have worse motor, cognitive, and language skills and more vision abnormalities than children without ROP.

Methods

This was a secondary analysis of a randomized trial evaluating the effects of myo-inositol on ROP in the NICHD Neonatal Research Network. Primary outcomes were Bayley Scales of Infant Development composite scores; secondary outcomes included behavioral difficulties and ophthalmologic measures. Outcomes were compared using adjusted linear or modified Poisson models.

Results

Of 506 children, 173 (34%) ha

SUBMITTER: Brumbaugh JE 

PROVIDER: S-EPMC9023615 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature