Treatment and outcomes in undifferentiated and dedifferentiated endometrial carcinoma.

ABSTRACT:

Objective

Undifferentiated and dedifferentiated endometrial carcinoma is a rare type of uterine malignancy. This study assesses disease characteristics, treatment and survival outcomes in patients with undifferentiated and dedifferentiated endometrial carcinoma treated at BC Cancer.

Methods

All patients diagnosed with undifferentiated and dedifferentiated endometrial carcinoma between 2000 and 2019 at BC Cancer were reviewed centrally. Clinical, pathologic, treatment and outcomes were reviewed retrospectively. The Kaplan-Meier method was used to evaluate overall survival (OS) and disease-free survival (DFS). Multivariable analysis was performed using Cox regression analysis.

Results

Fifty-two patients were included, 33% had undifferentiated carcinoma and 67% dediffere

SUBMITTER: Hamilton SN 

PROVIDER: S-EPMC9024191 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature