Beyond HIV outbreaks: protocol, rationale and implementation of a prospective study quantifying the benefit of incorporating viral sequence clustering analysis into routine public health interventions.

ABSTRACT:

Introduction

HIV continues to have great impact on millions of lives. Novel methods are needed to disrupt HIV transmission networks. In the USA, public health departments routinely conduct contact tracing and partner services and interview newly HIV-diagnosed index cases to obtain information on social networks and guide prevention interventions. Sequence clustering methods able to infer HIV networks have been used to investigate and halt outbreaks. Incorporation of such methods into routine, not only outbreak-driven, contact tracing and partner services holds promise for further disruption of HIV transmissions.

Methods and analysis

Building on a strong academic-public health collaboration in Rhode Island, we designed and have implemented a state-wide prospective study to ev

SUBMITTER: Steingrimsson JA 

PROVIDER: S-EPMC9024226 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature