Positive and Negative Symptoms Are Associated with Distinct Effects on Predictive Saccades.

ABSTRACT: The predictive saccade task is a motor learning paradigm requiring saccades to track a visual target moving in a predictable pattern. Previous research has explored extensively anti-saccade deficits observed across psychosis, but less is known about predictive saccade-related mechanisms. The dataset analysed came from the studies of Crawford et al, published in 1995, where neuroleptically medicated schizophrenia and bipolar affective disorder patients were compared with non-medicated patients and control participants using a predictive saccade paradigm. The participant groups consisted of medicated schizophrenia patients (n = 40), non-medicated schizophrenia patients (n = 18), medicated bipolar disorder patients (n = 14), non-medicated bipolar disorder patients (n</

SUBMITTER: Smith ES 

PROVIDER: S-EPMC9025332 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature