Evaluation of Antimicrobial and Anti-Biofilm Formation Activities of Novel Poly(vinyl alcohol) Hydrogels Reinforced with Crosslinked Chitosan and Silver Nano-Particles.

ABSTRACT: Novel hydrogels were prepared by blending chitosan and poly(vinyl alcohol), PVA, then crosslinking the resulting blends using trimellitic anhydride isothiocyanate at a concentration based on chitosan content in the blends. The weight ratios of chitosan: PVA in the blends were 1:3, 1:1, and 3:1 to produce three hydrogels symbolized as H₁₃, H₁₁, and H₃₁, respectively. For a comparison, H₁₀ was also prepared by crosslinking pure chitosan with trimellitic anhydride isothiocyanate. For further modification, three H₃₁/silver nanocomposites (AgNPs) were synthesized using three different concentrations of silver nitrate to obtain H₃₁/AgNPs1%, H₃₁/AgNPs3% and H₃₁/AgNPs5%. The structures of the prepared samples w

SUBMITTER: Alfuraydi RT 

PROVIDER: S-EPMC9026349 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature