Electroporation and Electrochemotherapy in Gynecological and Breast Cancer Treatment.

ABSTRACT: Gynecological carcinomas affect an increasing number of women and are associated with poor prognosis. The gold standard treatment plan is mainly based on surgical resection and subsequent chemotherapy with cisplatin, 5-fluorouracil, anthracyclines, or taxanes. Unfortunately, this treatment is becoming less effective and is associated with many side effects that negatively affect patients' physical and mental well-being. Electroporation based on tumor exposure to electric pulses enables reduction in cytotoxic drugs dose while increasing their effectiveness. EP-based treatment methods have received more and more interest in recent years and are the subject of a large number of scientific studies. Some of them show promising therapeutic potential without using any cytotoxic drugs or molecules

SUBMITTER: Lapinska Z 

PROVIDER: S-EPMC9026735 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature