Prevalence of ophthalmological manifestations in pediatric and adolescent populations with Down syndrome: a systematic review of the literature.

ABSTRACT:

Background

Down syndrome (DS) is a chromosomal anomaly that is characterized by an extra chromosome 21. Ophthalmological manifestations have a high prevalence in patients with DS.

Purpose

To review the scientific evidence and estimate the prevalence of ophthalmological manifestations in the pediatric population with DS.

Data sources

Electronic databases including MEDLINE, Cochrane Library, EMBASE, ScienceDirect, and LILACS.

Study eligibility criteria

Published observational studies with available and original data were included. Articles were excluded if the study design was a review, letter to the editor, case report, case series, or systematic review and if the subjects had ophthalmological manifestations secondary to other conditions.

Participants and int

SUBMITTER: Munoz-Ortiz J 

PROVIDER: S-EPMC9027460 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature