Secondary Metabolites in Basil, Bio-Insecticide, Inhibition Effect, and In Silico Molecular Docking against Proteolytic Enzymes of the Red Palm Weevil (Rhynchophorus ferrugineus).

ABSTRACT: The purpose of this work was to determine the secondary metabolites generated by O. basilicum cell suspensions, as well as their insecticide and inhibitory activity against R. ferrugineus. The growth kinetics with inoculation Verticillium dahliae were determined and identified using LC-MS. Determination of total phenolic components (TFC), flavonoids (TF), and condensed tannins (TCT) were measured. Insecticidal activity of O. basilicum extract against R. ferrugineus (larva and adult) and proteolytic enzymes activity were assessed (in vitro and in vivo). The O.basilicum extract had an LC₅₀ of 1238 µg/mL and an LD₅₀ of 13.4 µg/larva. The LC₅₀ of chicoric acid, ursolic acid, salvigenin, quercetin-3-O-rutinoside,

SUBMITTER: Darrag HM 

PROVIDER: S-EPMC9027599 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature