Topical Application of Antrodia cinnamomea Ointment in Diabetic Wound Healing.

ABSTRACT: The number of diagnosed diabetic patients is increasing worldwide. Many people with diabetes develop wounds that are slow to, or never, heal, which can lead to serious health issues. Diabetes causes long-term excessive blood glucose buildup in human body, which leads to an over-reactive inflammatory response and excessive oxidative stress. As a result, varied wound healing effects were observed according to different circumstances and stage of healing. We used two diabetic wound animal models to analyze the wound healing effect of Antrodia cinnamomea ointment in either topical application and/or oral administration, and explored its mechanism by Western blot analysis. The results showed that topical Antrodia cinnamomea treatment can significantly promote wound healing. The in

SUBMITTER: Su RC 

PROVIDER: S-EPMC9027955 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature