Snake Venomics: Fundamentals, Recent Updates, and a Look to the Next Decade.

ABSTRACT: Venomic research, powered by techniques adapted from proteomics, transcriptomics, and genomics, seeks to unravel the diversity and complexity of venom through which knowledge can be applied in the treatment of envenoming, biodiscovery, and conservation. Snake venom proteomics is most extensively studied, but the methods varied widely, creating a massive amount of information which complicates data comparison and interpretation. Advancement in mass spectrometry technology, accompanied by growing databases and sophisticated bioinformatic tools, has overcome earlier limitations of protein identification. The progress, however, remains challenged by limited accessibility to samples, non-standardized quantitative methods, and biased interpretation of -omic data. Next-generation sequencing (NGS)

SUBMITTER: Tan CH 

PROVIDER: S-EPMC9028316 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature