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A New Pyrroloquinoline-Derivative-Based Fluorescent Probe for the Selective Detection and Cell Imaging of Lysine.


ABSTRACT: In this paper, a new pyrroloquinoline-derivative-based fluorescent probe, PQP-1, was prepared for the selective detection of Lys in living cells and natural mineral water for drinking. PQP-1 exhibited high selectivity, low limit of detection, and a wide pH range. PQP-1 could be successfully applied for imaging Lys in living cells and in natural mineral water for drinking. We expect that PQP-1 will expand the detection reaction mechanism and the practical biological applications of Lys.

SUBMITTER: Yang B 

PROVIDER: S-EPMC9029482 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature

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A New Pyrroloquinoline-Derivative-Based Fluorescent Probe for the Selective Detection and Cell Imaging of Lysine.

Yang Bing B   Zhou Jiahua J   Huang Xu X   Chen Zhongping Z   Tian Shu S   Shi Yujun Y  

Pharmaceuticals (Basel, Switzerland) 20220413 4


In this paper, a new pyrroloquinoline-derivative-based fluorescent probe, <b>PQP-1</b>, was prepared for the selective detection of Lys in living cells and natural mineral water for drinking. <b>PQP-1</b> exhibited high selectivity, low limit of detection, and a wide pH range. <b>PQP-1</b> could be successfully applied for imaging Lys in living cells and in natural mineral water for drinking. We expect that <b>PQP-1</b> will expand the detection reaction mechanism and the practical biological ap  ...[more]

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