Serum Allergen-Specific IgE among Pediatric Patients with Primary Immunodeficiency.

ABSTRACT: Allergy is a clinical condition that reflects a deviated function of the immune system. The purpose of this study was to evaluate serum allergen-specific IgE (sIgE) along with clinical manifestations of allergy in patients with diagnosed primary immunodeficiency (PID). 72 patients, aged 1-17 years, diagnosed with PID and hospitalized between July 2020 and February 2021 were included in the study. Blood samples were obtained by venipuncture. sIgE (30 allergens), blood eosinophil count, as well as total IgE and IgG were measured and assessed in relation to a detailed medical examination. Serum sIgE was detected in the blood of 50% of the patients in the study group, which significantly correlated (p < 0.0001) with clinical symptoms of allergy. During the period of the study, 61.1% of the

SUBMITTER: Pieniawska-Smiech K 

PROVIDER: S-EPMC9029572 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature