Physical Activity and Its Diurnal Fluctuations Vary by Non-Motor Symptoms in Patients with Parkinson's Disease: An Exploratory Study.

ABSTRACT:

Background

This exploratory study investigated the association between non-motor symptoms (NMS) and both physical activity and diurnal activity patterns in patients with Parkinson's disease (PwPD).

Methods

Participants included PwPD with modified Hoehn and Yahr stages 1-3. The presence of NMS was assessed with Movement Disorder Society-Unified Parkinson's Disease Rating Scale (MDS-UPDRS) Part I. Physical activity was measured using a waist-mounted triaxial accelerometer. Logistic regression analyses evaluated associations between NMS and physical activity; furthermore, diurnal fluctuation in physical activity due to NMS was examined by ANCOVA.

Results

Forty-five PwPD were included in the study. Among the domains of NMS, pain and other sensations (OR, 8.36; 95% CI, 1.5

SUBMITTER: Nagaki K 

PROVIDER: S-EPMC9029803 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature