Metabolomic Approaches for Detection and Identification of Biomarkers and Altered Pathways in Bladder Cancer.

ABSTRACT: Metabolomic analysis has proven to be a useful tool in biomarker discovery and the molecular classification of cancers. In order to find new biomarkers, and to better understand its pathological behavior, bladder cancer also has been studied using a metabolomics approach. In this article, we review the literature on metabolomic studies of bladder cancer, focusing on the different available samples (urine, blood, tissue samples) used to perform the studies and their relative findings. Moreover, the multi-omic approach in bladder cancer research has found novel insights into its metabolic behavior, providing excellent start-points for new diagnostic and therapeutic strategies. Metabolomics data analysis can lead to the discovery of a "signature pathway" associated with the progression of bla

SUBMITTER: di Meo NA 

PROVIDER: S-EPMC9030452 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature