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ABSTRACT: Background
With advancing age the brain becomes more sensitive to centrally acting drugs thus increasing the risk of cognitive side-effects. The Swedish National Board of Health and Welfare developed indicators to measure and follow quality in older people's drug therapy, one being "Potentially Inappropriate Medications risking Cognitive impairment (PIMcogn)". Associations between anticholinergics and cognitive impairment are described, especially in persons with Alzheimer's disease or Lewy Body Dementia/Parkinson's disease dementia, due to degenerated cholinergic pathways.Objectives
To examine the prevalence of PIMcogn and if it differed between nursing home residents with and without a dementia diagnosis and between residents with different dementia aetiologias.Method
SUBMITTER: Kristensson JH
PROVIDER: S-EPMC9031036 | biostudies-literature | 2021 Sep
REPOSITORIES: biostudies-literature