Differential Gene Expression of Mucor lusitanicus under Aerobic and Anaerobic Conditions.

ABSTRACT: Mucor lusitanicus and some other members of the fungal order Mucorales display the phenomenon of morphological dimorphism. This means that these fungi aerobically produce filamentous hyphae, developing a coenocytic mycelium, but they grow in a multipolar yeast-like form under anaerobiosis. Revealing the molecular mechanism of the reversible yeast-hyphal transition can be interesting for both the biotechnological application and in the understanding of the pathomechanism of mucormycosis. In the present study, transcriptomic analyses were carried out after cultivating the fungus either aerobically or anaerobically revealing significant changes in gene expression under the two conditions. In total, 539 differentially expressed genes (FDR < 0.05, |log₂FC| ≥ 3) were identif

SUBMITTER: Homa M 

PROVIDER: S-EPMC9031258 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature