The Effect of Discharge Mode on the Distribution of Myocardial Pulsed Electric Field-A Simulation Study for Pulsed Field Ablation of Atrial Fibrillation.

ABSTRACT:

Background

At present, the effects of discharge modes of multielectrode catheters on the distribution of pulsed electric fields have not been completely clarified. Therefore, the control of the distribution of the pulsed electric field by selecting the discharge mode remains one of the key technical problems to be solved.

Methods

We constructed a model including myocardium, blood, and a flower catheter. Subsequently, by setting different positive and ground electrodes, we simulated the electric field distribution in the myocardium of four discharge modes (A, B, C, and D) before and after the catheter rotation and analyzed their mechanisms.

Results

Modes B, C, and D formed a continuous circumferential ablation lesion without the rotation of the catheter, with depths of

SUBMITTER: Ji X 

PROVIDER: S-EPMC9031694 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature