Prenatal Phthalate Exposure and Child Weight and Adiposity from in Utero to 6 Years of Age.

ABSTRACT:

Background

Prenatal phthalate exposure has been associated with lower birth weight but also higher weight in childhood. Few studies have examined weight or adiposity from birth to childhood and thus cannot assess growth trajectories associated with exposure.

Objective

We assessed associations between maternal phthalate exposures in pregnancy and child weight and adiposity measured prenatally through childhood (3-6 years of age).

Methods

Within The Infant Development and the Environment Study (TIDES), a prospective pregnancy cohort, we analyzed a panel of phthalate metabolites in urine collected at two visits from early and late gestation (N=780). We estimated average phthalate metabolite associations with child weight z-scores from ∼20wk gestation (estimated by ultras

SUBMITTER: Ferguson KK 

PROVIDER: S-EPMC9031798 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature