Association of orthostatic blood pressure response with incident heart failure: The Framingham Heart Study.

ABSTRACT:

Importance

Orthostatic hypotension (OH) and hypertension (OHT) are aberrant blood pressure (BP) regulation conditions associated with higher cardiovascular disease risk. The relations of OH and OHT with heart failure (HF) risk in the community are unclear and there remains a paucity of data on the relations with HF subtypes [HF with reduced ejection fraction (HFrEF) and HF with preserved ejection fraction (HFpEF)].

Objective

Relate OH and OHT with HF risk and its subtypes.

Design

Prospective observational cohort.

Setting

Community-based individuals in the Framingham Heart Study Original Cohort.

Participants

1,914 participants (mean age 72 years; 1159 women) attending examination cycle 17 (1981-1984) followed until December 31, 2017 for incident HF or dea

SUBMITTER: Shrout TA 

PROVIDER: S-EPMC9032405 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature