Incident Rheumatoid Arthritis Following Statin Use: From the View of a National Cohort Study in Korea.

ABSTRACT: Safety issues regarding the potential risk of statins and incident rheumatoid arthritis (RA) have been raised, but the existing data are largely based on Caucasian populations, and continue to have biases and require further validation in Asian populations. Here, we aimed to verify the risk of RA depending on the duration of previous statin use and statin types using a large-scale, nationwide database. This study enrolled 3149 patients with RA and 12,596 matched non-RA participants from the national health insurance database (2002−2015), and investigated their statin prescription histories for two years before the index date. Propensity score overlap-weighted logistic regression was applied after adjusting for multiple covariates. The prior use of any statins and, specifically, the long-te

SUBMITTER: Kwon MJ 

PROVIDER: S-EPMC9032630 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature