The Status and Prospects of Epigenetics in the Treatment of Lymphoma.

ABSTRACT: The regulation of gene transcription by epigenetic modifications is closely related to many important life processes and is a hot research topic in the post-genomic era. Since the emergence of international epigenetic research in the 1990s, scientists have identified a variety of chromatin-modifying enzymes and recognition factors, and have systematically investigated their three-dimensional structures, substrate specificity, and mechanisms of enzyme activity regulation. Studies of the human tumor genome have revealed the close association of epigenetic factors with various malignancies, and we have focused more on mutations in epigenetically related regulatory enzymes and regulatory recognition factors in lymphomas. A number of studies have shown that epigenetic alterations are indeed wid

SUBMITTER: Liu J 

PROVIDER: S-EPMC9033274 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature