Molecular mechanism of direct electron transfer in the robust cytochrome-functionalised graphene nanosystem.

ABSTRACT: Construction of green nanodevices characterised by excellent long-term performance remains high priority in biotechnology and medicine. Tight electronic coupling of proteins to electrodes is essential for efficient direct electron transfer (DET) across the bio-organic interface. Rational modulation of this coupling depends on in-depth understanding of the intricate properties of interfacial DET. Here, we dissect the molecular mechanism of DET in a hybrid nanodevice in which a model electroactive protein, cytochrome c ₅₅₃ (cyt c ₅₅₃), naturally interacting with photosystem I, was interfaced with single layer graphene (SLG) via the conductive self-assembled monolayer (SAM) formed by pyrene-nitrilotriacetic acid (pyr-NTA) molecules chelated to transi

SUBMITTER: Jacquet M 

PROVIDER: S-EPMC9033600 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature