A novel 5-ring multifocal electroretinography stimulus for detecting hydroxychloroquine retinal toxicity.

ABSTRACT:

Purpose

Multifocal electroretinogram (mfERG) shows great utility as a screening tool to detect early hydroxychloroquine (HCQ) retinopathy, but its widespread use is limited by the lack of accessibility and long test duration. In this study, we evaluated a novel concentric 5-ring mfERG stimulus to provide a simplified and rapid protocol for screening HCQ toxicity.

Methods

Patients referred for HCQ retinopathy screening were consented to this observational cross-sectional study. Patients with amblyopia, high refractive error (more than 8 diopters), other retinal diseases precluding appropriate evaluation or history of retinal surgery were excluded. The data were collected from patients undergoing HCQ screening at a single center from July 2019 to March 2020. Patients were test

SUBMITTER: Tsang A 

PROVIDER: S-EPMC9033700 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature