The rationality of using core-shell nanoparticles with embedded internal standards for SERS quantitative analysis based glycerol-assisted 3D hotspots platform.

ABSTRACT: Surface enhanced Raman spectroscopy (SERS) is a promising sensing technique that can provide unique chemical and structural fingerprint information, but gaining reliable SERS quantitative data with high sensitivity and stability still remains a challenge. Although using a molecule as an internal standard (IS) can improve the SERS quantitative capability, the reliability and SERS measuring conditions for signal fluctuations during calibration based on IS are yet to be explored when the embedded IS molecules and target objects are located in different environments. Herein, a 3D hotspot matrix SERS platform based on Au@4-MPy@AgNPs was constructed in water with the assistance of glycerol and the dynamic signal changes from the IS, i.e. 4-Mpy, and target molecules were monitored during t

SUBMITTER: Wang XA 

PROVIDER: S-EPMC9033995 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature