Effect of red beetroot juice on oxidative status and islet insulin release in adult male rats.

ABSTRACT:

Introduction

Beetroot is rich in inorganic nitrate and it has been shown that inorganic nitrate has beneficial effects on metabolic syndrome. This study aims to investigate the effect of red beetroot juice (RBJ) on carbohydrate metabolism in adult insulin-resistant rats.

Materials and methods

Sixteen male Wistar rats (32 weeks old) were divided into two equal groups: control and RBJ. Treatment with drinking water (control) and 100% RBJ (RBJ) was lasted for 5 weeks. At the end of the 4th week the intraperitoneal glucose tolerance test was performed and at the end of the study period animals were sacrificed and blood and tissue (aorta, heart, and liver) samples were collected. Furthermore, pancreatic islets were isolated and their insulin secretion activity was investigated in

SUBMITTER: Sayyar A 

PROVIDER: S-EPMC9034606 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature