Impact of Reference Center Choice on Adaptive Optics Imaging Cone Mosaic Analysis.

ABSTRACT:

Purpose

Foveal center marking is a key step in retinal image analysis. We investigated the discordance between the adaptive optics (AO) montage center (AMC) and the foveal pit center (FPC) and its implications for cone mosaic analysis using a commercial flood-illumination AO camera.

Methods

Thirty eyes of 30 individuals (including 15 healthy and 15 patients with rod-cone dystrophy) were included. Spectral-domain optical coherence tomography was used to determine the FPC, and flood-illumination AO imaging was performed with overlapping image frames to create an AO montage. The AMC was determined by averaging the (0,0) coordinates in the four paracentral overlapping AO image frames. Cone mosaic measurements at various retinal eccentricities were compared between corresponding

SUBMITTER: Roshandel D 

PROVIDER: S-EPMC9034713 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature