Association Between Fluid Volume in Inner Nuclear Layer and Visual Acuity in Diabetic Macular Edema.

ABSTRACT:

Purpose

In diabetic macular edema (DME), the correlation between visual acuity (VA) and central subfield thickness (CST) is weak. We hypothesize that fluid volume (FV) in the inner nuclear layer (INL) may correlate more strongly with VA.

Design

Retrospective, cross-sectional study.

Methods

One eye each of diabetic patients with DME was included. We measured intraretinal fluid volume that was detected by automated fluid detection algorithm on 3- × 3-mm optical coherence tomography angiogram volume scans. The detected fluid was subdivided into inner FV, bounded by the INL, and outer FV, the fluid between the outer border of INL to the ellipsoid zone.

Results

We enrolled 125 patients with DME (60 women; mean age, 61 years). The mean detected inner FV was 0.013 mm<

SUBMITTER: Tsuboi K 

PROVIDER: S-EPMC9035073 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature