Characterization of The Retinal Progenitor Cells Generated Using Co-Culture Systems.

ABSTRACT:

Objective

Degeneration of the photoreceptors due to retinal disorders can affect vision, and even lead to blindness. Recently therapeutic progress in retinal degeneration, using human embryonic stem cells (hESCs), has been facing technical challenges, demanding the development of simple and standardized protocols. In addition to the designing of the protocols, characterization of the obtained cells is highly required for confirming the reliability of the applied methods for future medical applications. Previously, we showed that human stem cells from apical papilla (SCAP) have stromal cell-derived inducing activity (SDIA).

Materials and methods

In this experimental study, we developed an efficient retinal differentiation protocol, based on the co-culture of confluent hESCs a

SUBMITTER: Momenzadeh S 

PROVIDER: S-EPMC9035232 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature