Association between Mycobacterium tuberculosis genotype and diabetes mellitus/hypertension: a molecular study.

ABSTRACT:

Background

A paucity of studies focused on the genetic association that tuberculosis (TB) patients with non-communicable diseases (NCDs) are more likely to be infected with Mycobacterium tuberculosis (MTB) with more potent virulence on anti-TB drug resistance than those without NCDs. The study aimed to document the predominant genotype, determine the association between MTB genotypes and NCD status and drug resistance.

Methods

We conducted a molecular study in 105 TB patients based on a cross-sectional study focused on the comorbid relationship between chronic conditions and TB among 1773 subjects from September 1, 2019 to August 30, 2020 in Guizhou, China. The participants were investigated through face-to-face interviews, followed by NCDs screening. The DNA of MTB isolates

SUBMITTER: Guo S 

PROVIDER: S-EPMC9035274 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature