Enhance the delivery of light energy ultra-deep into turbid medium by controlling multiple scattering photons to travel in open channels.

ABSTRACT: Multiple light scattering is considered as the major limitation for deep imaging and focusing in turbid media. In this paper, we present an innovative method to overcome this limitation and enhance the delivery of light energy ultra-deep into turbid media with significant improvement in focusing. Our method is based on a wide-field reflection matrix optical coherence tomography (RM-OCT). The time-reversal decomposition of the RM is calibrated with the Tikhonov regularization parameter in order to get more accurate reversal results deep inside the scattering sample. We propose a concept named model energy matrix, which provides a direct mapping of light energy distribution inside the scattering sample. To the best of our knowledge, it is the first time that a method to measure and quantify

SUBMITTER: Cao J 

PROVIDER: S-EPMC9035453 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature