Large-scale functional brain networks of maladaptive childhood aggression identified by connectome-based predictive modeling.

ABSTRACT: Disruptions in frontoparietal networks supporting emotion regulation have been long implicated in maladaptive childhood aggression. However, the association of connectivity between large-scale functional networks with aggressive behavior has not been tested. The present study examined whether the functional organization of the connectome predicts severity of aggression in children. This cross-sectional study included a transdiagnostic sample of 100 children with aggressive behavior (27 females) and 29 healthy controls without aggression or psychiatric disorders (13 females). Severity of aggression was indexed by the total score on the parent-rated Reactive-Proactive Aggression Questionnaire. During fMRI, participants completed a face emotion perception task of fearful and calm faces. Conne

SUBMITTER: Ibrahim K 

PROVIDER: S-EPMC9035467 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature