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The gut microbiome as a modulator of healthy ageing.


ABSTRACT: The gut microbiome is a contributory factor in ageing-related health loss and in several non-communicable diseases in all age groups. Some age-linked and disease-linked compositional and functional changes overlap, while others are distinct. In this Review, we explore targeted studies of the gut microbiome of older individuals and general cohort studies across geographically distinct populations. We also address the promise of the targeted restoration of microorganisms associated with healthier ageing.

SUBMITTER: Ghosh TS 

PROVIDER: S-EPMC9035980 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature

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The gut microbiome as a modulator of healthy ageing.

Ghosh Tarini Shankar TS   Shanahan Fergus F   O'Toole Paul W PW  

Nature reviews. Gastroenterology & hepatology 20220425 9


The gut microbiome is a contributory factor in ageing-related health loss and in several non-communicable diseases in all age groups. Some age-linked and disease-linked compositional and functional changes overlap, while others are distinct. In this Review, we explore targeted studies of the gut microbiome of older individuals and general cohort studies across geographically distinct populations. We also address the promise of the targeted restoration of microorganisms associated with healthier  ...[more]

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