Association of healthy lifestyle and all-cause mortality according to medication burden.

ABSTRACT:

Background

Healthy lifestyle is associated with reduced all-cause mortality, but it is not known whether this association persists for individuals with high medication burden. We examined the association between healthy lifestyle behaviors and all-cause mortality across different degrees of polypharmacy.

Methods

This was a secondary analysis of 20,417 adults aged ≥45 years from the Reasons for Geographic and Racial Differences in Stroke (REGARDS) cohort study. The primary exposure was healthy lifestyle (adherence to Mediterranean diet, physical activity, smoking abstinence, sedentary behavior avoidance, and composite healthy behavior score [HBS]). The primary outcome was all-cause mortality. Strata of medication burden were based on the number of medications taken (no polyph

SUBMITTER: Kelly NA 

PROVIDER: S-EPMC9036408 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature