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Copper-catalyzed transformation of alkyl nitriles to N-arylacetamide using diaryliodonium salts.

ABSTRACT: This work reports a simple and efficient method for the copper-catalyzed redox-neutral transformation of alkyl nitriles using eco-friendly diaryliodonium salts and leading to N-arylacetamides. The method features high efficiency, broad substrate scope and good functional group tolerance.

SUBMITTER: Sallio R

PROVIDER: S-EPMC9036411 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature

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Copper-catalyzed transformation of alkyl nitriles to N-arylacetamide using diaryliodonium salts.

Sallio Romain R Payard Pierre-Adrien PA Pakulski Paweł P Diachenko Iryna I Fabre Indira I Berteina-Raboin Sabine S Colas Cyril C Ciofini Ilaria I Grimaud Laurence L Gillaizeau Isabelle I

RSC advances 20210428 26

This work reports a simple and efficient method for the copper-catalyzed redox-neutral transformation of alkyl nitriles using eco-friendly diaryliodonium salts and leading to N-arylacetamides. The method features high efficiency, broad substrate scope and good functional group tolerance. ...[more]

PMID: 35481165

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