Establishing the reference interval for pulse oxygen saturation in neonates at high altitudes: protocol for a multicentre, open, cross-sectional study.

ABSTRACT:

Introduction

Establishing the reference interval for pulse oxygen saturation (SpO₂) is essential for sensitively identifying neonatal hypoxaemia due to various causes. However, the reference interval for high altitudes has not yet been established, and existing studies have many limitations. This study will aim to establish the reference interval for various high altitudes and determine whether preductal and postductal measurements at the same altitude vary.

Methods and analysis

This is a multicentre, open, cross-sectional study, which will begin in February 2022. Approximately 2000 healthy full-term singleton neonates will be recruited from six hospitals (altitude ≥2000 m) in Qinghai Province, China. The participating hospitals will use a uniform pulse oximeter t

SUBMITTER: Wang B 

PROVIDER: S-EPMC9036428 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature