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Advances in our understanding of the molecular pathogenesis of necrotizing enterocolitis.


ABSTRACT: Necrotizing enterocolitis (NEC) is a multifactorial and complex disease. Our knowledge of the cellular and genetic basis of NEC have expanded considerably as new molecular mechanisms have been identified. This article will focus on the current understanding of the molecular pathogenesis of NEC with a focus on the inflammatory, immune, infectious, and genetic mechanisms that drive disease development.

SUBMITTER: Cai X 

PROVIDER: S-EPMC9036771 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature

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Advances in our understanding of the molecular pathogenesis of necrotizing enterocolitis.

Cai Xue X   Golubkova Alena A   Hunter Catherine J CJ  

BMC pediatrics 20220425 1


Necrotizing enterocolitis (NEC) is a multifactorial and complex disease. Our knowledge of the cellular and genetic basis of NEC have expanded considerably as new molecular mechanisms have been identified. This article will focus on the current understanding of the molecular pathogenesis of NEC with a focus on the inflammatory, immune, infectious, and genetic mechanisms that drive disease development. ...[more]

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